Dr. Felipe Fregni, MD PhD MPH 

Director of Research, Spaulding-Harvard SCIMS

Felipe Fregni (MD, PhD, MPH), is the Director of the Laboratory of Neuromodulation at Spaulding Rehabilitation Hospital, Harvard Medical School, as well as an Associate Professor of Neurology and Physical Medicine and Rehabilitation at Harvard Medical School, Boston, MA, USA. He is also the course director for the HMS continuing medical education course, Principles and Practice of Clinical Research, a 6-month distance learning course. It focuses on promoting collaboration and bringing clinical research education to practicing clinicians worldwide.


Research Interests: Currently, his research is focused on understanding neuroplastic changes associated with conditions such as chronic pain, Parkinson’s disease, and stroke, using non-invasive brain stimulation as an investigative tool for such aims. In addition, his laboratory is comprised of about 15 research fellows and staff, and is a training center for clinical research and neuromodulation methodology. Dr. Fregni’s laboratory is funded by several sponsors including NIH, the Christopher and Dana Reeve Foundation, CIMIT, and the RJG Foundation. More information can be found at his laboratory website, www.neuromodulationlab.org


Recent Publications:

Gladwin TE, den Uyl TE, Fregni F, Wiers RW. Enhancement of selective attention by tDCS: Interaction with interference in a Sternberg task. Neurosci Lett. 2012 Feb 2. [Epub ahead of print] PubMed PMID: 22327036.

Plow EB, Obretenova SN, Fregni F, Pascual-Leone A, Merabet LB. Comparison of Visual Field Training for Hemianopia With Active Versus Sham Transcranial Direct Cortical Stimulation. Neurorehabil Neural Repair. 2012 Jan 30. [Epub ahead of print] PubMed PMID: 22291042.

Riberto M, Marcon Alfieri F, Monteiro de Benedetto Pacheco K, Dini Leite V, Nemoto Kaihami H, Fregni F, Rizzo Battistella L. Efficacy of transcranial direct  current stimulation coupled with a multidisciplinary rehabilitation program for the treatment of fibromyalgia. Open Rheumatol J. 2011;5:45-50. Epub 2011 Oct 18.  PubMed PMID: 22046206; PubMed Central PMCID: PMC3204430.

Brunoni AR, Nitsche MA, Bolognini N, Bikson M, Wagner T, Merabet L, Edwards DJ, Valero-Cabre A, Rotenberg A, Pascual-Leone A, Ferrucci R, Priori A, Boggio PS, Fregni F. Clinical research with transcranial direct current stimulation (tDCS): Challenges and future directions. Brain Stimul. 2011 Apr 1. [Epub ahead of print] PubMed PMID: 22037126; PubMed Central PMCID: PMC3270156.

Campanhã C, Minati L, Fregni F, Boggio PS. Responding to unfair offers made by a friend: neuroelectrical activity changes in the anterior medial prefrontal cortex. J Neurosci. 2011 Oct 26;31(43):15569-74. PubMed PMID: 22031902.

Faber M, Vanneste S, Fregni F, De Ridder D. Top down prefrontal affective modulation of tinnitus with multiple sessions of tDCS of dorsolateral prefrontal cortex. Brain Stimul. 2011 Oct 5. [Epub ahead of print] PubMed PMID: 22019079.

Ladeira A, Fregni F, Campanhã C, Valasek CA, De Ridder D, Brunoni AR, Boggio PS. Polarity-dependent transcranial direct current stimulation effects on central auditory processing. PLoS One. 2011;6(9):e25399. Epub 2011 Sep 23. PubMed PMID: 21966519; PubMed Central PMCID: PMC3179516.

Brunoni AR, Valiengo L, Zanao T, de Oliveira JF, Bensenor IM, Fregni F. Manic psychosis after sertraline and transcranial direct-current stimulation. J Neuropsychiatry Clin Neurosci. 2011 Summer;23(3):E4-5. PubMed PMID: 21948925.

Boggio PS, Valasek CA, Campanhã C, Giglio AC, Baptista NI, Lapenta OM, Fregni F. Non-invasive brain stimulation to assess and modulate neuroplasticity in Alzheimer's disease. Neuropsychol Rehabil. 2011 Oct;21(5):703-16. Epub 2011 Sep 26. Review. PubMed PMID: 21942868.